eXplicit Content: A Discussion of the MPAA Film Rating System and the NC-17 Rating

The United States film industry is controlled by the Motion Picture Association of America (MPAA) and its six signatories--the major productions studios (Sony, Warner Brothers, Universal, Walt Disney, 20th Century Fox, Time Warner), and through this joint-partnership they have monopolized prime production, distribution, exhibition and classification of the U.S film market. The objective of this project is to shed light on biases present in the MPAA rating system\u27s treatment of sex and violence under the X/NC-17 rating in order to demonstrate the lack of viability of the system in today\u27s world

Department of Anatomy and Cell Biology Electron Microscopy Center In honor of the late Dr. V H Gattone, Director of the Electron Microcopy Center

poster abstractThe Indiana University School of Medicine Electron Microscopy Center is a full service research laboratory providing both Transmission and Scanning Electron Microscopy. The center can provide the technical services to help design and then implement experiments needing either type of microscopy. Free consultation with assistant director/lab manager is provided with any new experiment. The service provided can apply both traditional methods and more recent technical developments to suit the investigator's needs. The services that are available are: 1) Transmission Electron Microscopy (TEM). FEI Tecnai G2 12 Bio Twin (Hillsboro, OR) equipped with an AMT (Advanced Microscopy Techniques, Danvers, MA) CCD camera. Operating system, updated in 2013. Routine processing of specimens, fixation through embedding. Thick and thin sectioning with staining. Viewing and imaging on microscope. Various specimen types accepted, from tissue pieces to cell cultures either as a monolayer or cell pellet. Negative staining can be done on various specimens, such as virus, bacteria, exosomes or even hallosite crystals in clay. 2) Immunocytochemistry. This would include processing of specimens with a special fixative and embedding resin used for immunostaining, thick and thin sectioning, the immunostaining process, primary antibody provided by the researcher, secondary antibody provided by the EM Center. Viewing and imaging on the microscope. 3) Scanning Electron Microscopy (SEM). JEOL 6390 LV (Peabody, MA).Routine processing of specimens with fixation, critical point or chemical drying, mounting and sputter-coating. Viewing and imaging on the scope. 4) Field Emission Scanning Electron Microscopy (FE SEM). JEOL JSM-7800F (Peabody, MA). Brand new for 2014. Extreme high resolution analytical thermal field emission scanning electron microscope, it is a current production state-of-art fourth generation high resolution in-lens gun field emission electron microscope. 1.0nm resolution, at 15KV. Magnification range from 25x-1,000,000x. Routine processing of specimens with fixation, critical point or chemical drying, mounting and carbon coating. Viewing and imaging on the scope. Fee schedule and contact information available on the website. See below and please feel free to contact Caroline Miller with any questions you have related to electron microscopy. http://anatomy.iupui.edu/core-facilities/electron-microscopy-center

Structure theorems for ordered groupoids

The Ehresmann-Schein-Nambooripad theorem, which states that the category of inverse semigroups is isomorphic to the category of inductive groupoids, suggests a route for the generalisation of ideas from inverse semigroup theory to the more general setting of ordered groupoids. We use ordered groupoid analogues of the maximum group image and the E-unitary property – namely the level groupoid and incompressibility – to address structural questions about ordered groupoids. We extend the definition of the Margolis-Meakin graph expansion to an expansion of an ordered groupoid, and show that an ordered groupoid and its expansion have the same level groupoid and that the incompressibility of one determines the incompressibility of the other. We give a new proof of a P-theorem for incompressible ordered groupoids based on the Cayley graph of an ordered groupoid, and also use Ehresmann’s Maximum Enlargement Theorem to prove a generalisation of the P-theorem for more general immersions of ordered groupoids. We then carry out an explicit comparison between the Gomes-Szendrei approach to idempotent pure maps of inverse semigroups and our construction derived from the Maximum Enlargement Theorem.Caledonian Research Foundation Scholarshi

The Expression Of Connexin-43 By CD11c+ Dendritic Cells Is Required to Maintain CD4+ Foxp3+ Regulatory T Cell Population in Peripheral Lymphoid Organs

Foxp3+ regulatory T cells (TR) are an immunosuppressive subset of CD4+ T cells that maintain homeostasis of the immune system. They are sustained by the interaction between the Major Histocompatibility Complex (MHC) molecules present on antigen presenting dendritic cells and the T Cell Receptor (TCR) expressed on TR cells that is specific for the MHC loaded with an antigenic peptide. Here, we show that in addition to MHC/TCR interaction, Connexin-43 (Cx43) expression by dendritic cells is required to maintain the TR cell population. CD11c+ dendritic cells represent a major subset of antigen presenting cells. Using flow cytometry, we have observed that mice which lack Cx43 expression in CD11c+ dendritic cells (Cx43DC-), have a lower percentage of TR cells which express lower levels of Foxp3. These mice showed increased incidence of dermatitis as they age, even though we show that their dendritic cells can efficiently present antigen to naive T cells using proliferation inhibition assay. The decrease in the proportion of TR cells were associated with an altered phenotype of these cells, demonstrated by lower expression of CD39 and higher expression of CD73, ectonucleotidases mediating TR cell immunosuppressive function. We propose that the presence of Cx43 on the surface of dendritic cells is required for effective communication between TR cells and dendritic cells so as to sustain TR cell homeostatic expansion and Foxp3 expression

Morristown Montessori preschool

In many cases, a child\u27s first real contact with the built environment beyond the home is the preschool. This building type has been too often ignored in recent years. This thesis will explore how the built environment can engage a child and support his/her early education. I have chosen to explore these issues through the design investigation of a Montessori approach to early childhood education. I have investigated the design for this curricular approach because Montessori educational objectives, pedagogy, and focus are on nurturing and engaging the development of the child through active and independent involvement with his/her environment and are thus compatible with this thesis investigation

The millennial generation reshaping the workplace: what changes are needed for organizations to attract and retain employees ?

This report aims to measure how different is the Millennial generation from the Western world from their predecessors and identify ways in which firms should adapt in order to attract and retain these new talents. These recommendations will not only take into account generational aspects of this challenge, but also the overall environment and the different forces shaping the future of work. Two main challenges are to be linked with this generation in the workplace. The first one lies in the fact that the Millennial generation does not have the same expectations, needs and ambitions from a career. The second challenge is the cohabitation of four generations in the workplace, which will be challenging as they will not have a common language to speak with and could result in conflictual situations due to their differences. In order to answer to these identified challenges and for my recommendations to be viable, this work’s introduction set the overall context used to understand the global future of work, the different aspects of a firm’s structure and finally a thorough analyse of each generation which will need to collaborate in the workplace, namely the Baby-boomers, Generation X and the Millennials. The second part of this thesis analyses the results from my qualitative and quantitative research on the subject. The qualitative research represents four different interviews of firms from different industries and the qualitative research has been done through a survey sent to the particular Millennial population of Swiss apprentices, in order to complete the very thorough Deloitte research on Millennials, which does not take into account this population. Finally, my recommendations highlight how firms can adapt various aspects of their internal organization in order to attract and retain the talents of this Millennial generation, but also survive in the workplace of the future